Some letter pairs are quite common in English words - such as ST, SH, CR, BR at the start of the word; and LY, SE, TY, TE at the end of the word. So, when you see these letters in adjacent columns, look out for possibilities to pair them together.
But when employing this strategy, it's best to start out with the uncommon letters first. For example, if B appears in the first column, and C, V, A, L, T are in the second column, you can be sure that the letter after B will be A or L (because English words don't begin with BC, BV or BT). Now if another letter in the first column is W, then you know that the A from the second column must be paired with the W (because WC, WV, WL and WT are not possible). Which means that the B cannot be paired with the A afterall (as it belongs with the W) so the only remaining possibility is for the B to be paired with the L.
In a similar vein, if there is a Q in your puzzle, then you can be assured that a U in the right-adjacent column belongs to the Q, even if it fits perfectly for another word!